ĶOS713 Bioorganic Chemistry

Code ĶOS713
Name Bioorganic Chemistry
Status Compulsory/Courses of Limited Choice
Level and type Post-graduate Studies, Academic
Field of study Chemistry and Chemical Technology
Faculty Department of Chemical Technology of Biologically Active Compounds
Academic staff Irina Novosjolova, Ērika Bizdēna
Credit points 2.0 (3.0 ECTS)
Parts 1
Annotation In this course, attention is paid to the following topics: the main classes of biomolecules, their functions in organism. Methods of synthesis of L-amino acids. Chemical synthesis of peptides: protecting groups,coupling agents, strategy of synthesis. Synthesis of peptides in solution and on solid phase. Peptide synthesizers.Analysis of peptides.Methods for determination of protein structure. Methods of synthesis of nucleosides, nucleotides and their biologically active analogues.Synthesis of oligonucleotides and their analogues. Solid phase synthesis. Application of oligonucleotides in biology and medicine.. Organisation of genome. Genes. Sequencing of DNA. Types of cell lipids. Application of lipids for the modification of pharmaceuticals. Chemical synthesis of oligosaccharides. Insight in chemistry of bioconjugates, their application in medicine and cell biology..
Goals and objectives
of the course in terms
of competences and skills
Learning outcomes
and assessment

Course prerequisites

[Extended course information PDF]